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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pcp2tm1Jim
targeted mutation 1, James I Morgan
MGI:3579785
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pcp2tm1Jim/Pcp2tm1Jim involves: 129S1/Sv * C57BL/6J MGI:3579788


Genotype
MGI:3579788
hm1
Allelic
Composition		 Pcp2tm1Jim/Pcp2tm1Jim
Genetic
Background		 involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcp2tm1Jim mutation (0 available); any Pcp2 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:40442 )
• appeared normal at birth and developed through adulthood without any behavioral signs of cerebellar or retinal degeneration or dysfunction
• anatomically, cerebellar foliation and cortical structure was normal
• the cerebellar nuclei and brainstem structures that innervate the cerebellum, such as inferior olivary nucleus appeared normal
• number of Purkinje neuron were normal
• no evidence of any enhanced Purkinje cell loss in 1 year old mutant mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory