Phenotypes associated with this allele

• Allele Symbol: Aqp7^tm1Ask
• Allele Name: targeted mutation 1, A S Verkman
• Allele ID: MGI:3580002
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aqp7^tm1Ask/Aqp7^tm1Ask	involves: CD-1	MGI:3580307

Genotype
MGI:3580307

hm1

• Allelic Composition: Aqp7^tm1Ask/Aqp7^tm1Ask
• Genetic Background: involves: CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased fat cell size ( J:98734 )

• at 16 weeks average adipocyte area is increased and adipocyte diameter is increased about 3-fold

increased gonadal fat pad weight ( J:98734 )

• at 16 weeks of age the gonadal fat pad mass is significantly increased

abnormal white adipose tissue physiology ( J:98734 )

• adipocyte glycerol, free fatty acid, and triglyceride levels expressed on a per milligram of protein level are significantly increased; however serum levels in 16 week old mutants are normal

• glycerol uptake and glycerol release from adipocytes are significantly reduced; however, lipolysis is similar to wild-type

growth/size/body

decreased body length ( J:98734 )