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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Rarb-cre)1Bhr
transgene insertion 1, Richard R Behringer
MGI:3580294
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rxfp2tm1Aia/Rxfp2tm1c(EUCOMM)Wtsi
Tg(Rarb-cre)1Bhr/0 		involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6N * SJL MGI:5473318
cn2
 		Lhx1tm2.1Bhr/Lhx1tm1Tmj
Tg(Rarb-cre)1Bhr/0 		involves: 129S/SvEv * C57BL/6 * SJL MGI:3580503


Genotype
MGI:5473318
cn1
Allelic
Composition		 Rxfp2tm1Aia/Rxfp2tm1c(EUCOMM)Wtsi
Tg(Rarb-cre)1Bhr/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rxfp2tm1Aia mutation (0 available); any Rxfp2 mutation (53 available)
Rxfp2tm1c(EUCOMM)Wtsi mutation (0 available); any Rxfp2 mutation (53 available)
Tg(Rarb-cre)1Bhr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
cryptorchism ( J:194006 )
• high intra-abdominal cryptorchidism

endocrine/exocrine glands
cryptorchism ( J:194006 )
• high intra-abdominal cryptorchidism




Genotype
MGI:3580503
cn2
Allelic
Composition		 Lhx1tm2.1Bhr/Lhx1tm1Tmj
Tg(Rarb-cre)1Bhr/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx1tm1Tmj mutation (0 available); any Lhx1 mutation (22 available)
Lhx1tm2.1Bhr mutation (0 available); any Lhx1 mutation (22 available)
Tg(Rarb-cre)1Bhr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:98831 )
• died within the first day of birth

renal/urinary system
absent renal glomerulus ( J:98831 )
• absent glomeruli and their associated tubules in neonates
abnormal kidney development ( J:98831 )
• nephron development was arrested at the stage of the renal vesicle
abnormal kidney medulla development ( J:98831 )
• medulla was not correctly formed in neonates
small metanephros ( J:98831 )
• neonates had small metanephroi without nephrons but with normal ureters and normal reproductive tracts
absent nephron ( J:98831 )
• neonates had small metanephroi with no nephrons
abnormal urinary bladder morphology ( J:98831 )
• shrunken bladder with no urine




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory