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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Axin1tm1(Axin2)Cos
targeted mutation 1, Frank Costantini
MGI:3580422
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Axin1tm1(Axin2)Cos/Axin1tm1(Axin2)Cos involves: 129S6/SvEvTac * FVB/N MGI:3582067
ht2
Axin1Fu-Tg1/Axin1tm1(Axin2)Cos involves: 129S6/SvEvTac * C57BL/6J * CBA/J * FVB/N MGI:3582069


Genotype
MGI:3582067
hm1
Allelic
Composition
Axin1tm1(Axin2)Cos/Axin1tm1(Axin2)Cos
Genetic
Background
involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Axin1tm1(Axin2)Cos mutation (0 available); any Axin1 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice homozygous for a null mutation were fertile and had normal life span; no premature deaths, obvious behavioral defects or overt tumors were found
• difference of 11 to 14 % less in weight compared to wild-type control at birth to 28 days is observed; this difference was only 5 to 6% and was not statistically significant by 6 weeks




Genotype
MGI:3582069
ht2
Allelic
Composition
Axin1Fu-Tg1/Axin1tm1(Axin2)Cos
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J * CBA/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Axin1Fu-Tg1 mutation (1 available); any Axin1 mutation (44 available)
Axin1tm1(Axin2)Cos mutation (0 available); any Axin1 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice homozygous for a null mutation were fertile and had normal life span; no premature deaths, obvious behavioral defects or overt tumors are found





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory