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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Axin1tm2Cos
targeted mutation 2, Frank Costantini
MGI:3580423
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Axin1tm2Cos/Axin1tm2Cos involves: 129S6/SvEvTac * FVB/N MGI:3582068


Genotype
MGI:3582068
hm1
Allelic
Composition
Axin1tm2Cos/Axin1tm2Cos
Genetic
Background
involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Axin1tm2Cos mutation (0 available); any Axin1 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice homozygous for a null mutation were fertile and had normal life span; no premature deaths, obvious behavioral defects or overt tumors were found
• difference of 11 to 14 % less in weight compared to wild-type control at birth to 28 days is observed; this difference was only 5 to 6% and was not statistically significant by 6 weeks





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory