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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Tyr-cre)3Gfk
transgene insertion 3, Graham F Kay
MGI:3580525
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk
Tg(Tyr-cre)3Gfk/0
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) MGI:3580534


Genotype
MGI:3580534
cn1
Allelic
Composition
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk
Tg(Tyr-cre)3Gfk/0
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkar1atm1.2Lsk mutation (1 available); any Prkar1a mutation (19 available)
Tg(Tyr-cre)3Gfk mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• unilateral or bilateral tumors on the side of the face starting at 3 - 4 months
• tumors in subcutaneous tissue - Schwannomas

nervous system
• tumors in subcutaneous tissue - Schwannomas

growth/size/body
• unilateral or bilateral tumors on the side of the face starting at 3 - 4 months

craniofacial
• unilateral or bilateral tumors on the side of the face starting at 3 - 4 months

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Carney complex DOID:0050471 OMIM:160980
OMIM:605244
OMIM:608837
J:98799





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory