About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hrastm1Grnt
targeted mutation 1, Seth G N Grant
MGI:3580632
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hrastm1Grnt/Hrastm1Grnt involves: 129P2/OlaHsd MGI:3581303
cx2
 		Hrastm1Grnt/Hrastm1Grnt
Syngap1tm1Grnt/Syngap1+ 		involves: 129P2/OlaHsd * MF1 MGI:3581305


Genotype
MGI:3581303
hm1
Allelic
Composition		 Hrastm1Grnt/Hrastm1Grnt
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Grnt mutation (0 available); any Hras mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:98903 )
N
• 150 pulse trains of 5 Hz synaptic stimulation induced similar amounts of long term potentiation in the hippocampal CA1 region as in wildtype




Genotype
MGI:3581305
cx2
Allelic
Composition		 Hrastm1Grnt/Hrastm1Grnt
Syngap1tm1Grnt/Syngap1+
Genetic
Background		 involves: 129P2/OlaHsd * MF1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Grnt mutation (0 available); any Hras mutation (30 available)
Syngap1tm1Grnt mutation (0 available); any Syngap1 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:98903 )
• long term potentiation induced by 150 pulses of 5 Hz stimulation in the hippocampal CA1 region was reduced compared to wildtype and single homozygous Hras1 mutants




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory