Analysis Tools
immune system
hematopoietic system
behavior/neurological
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• females have difficulty nursing owing to a propensity for skin lesions
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integument
dermal cyst
(
J:156542
)
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• develop from keratinocyte remnants that surrounded the dermal papilla
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• hair loss beginning at ventrum at approximately 2.5 weeks of age and proceeding in a diffuse manner across the body
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• at 6 months of age mice display overgrown nails that curve under the foot pad (onychogryposis)
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• at 5 weeks of age as the follicle enters catagen, a thin serpentine-shaped band of cells, surrounded by a glassy membrane, extend from the abnormal ectatic infundibulum to the dilated deep dermal cyst
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• at 14 days hair infundibula are mildly ectatic and filled with laminated cornified cells
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• at 18 days dilation of the infundibulum is increased compared to control mice at 14 days of age
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• vibrissae become sparse with age
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• at 14 days stratum granulosum extends from the epidermis to the entrance of the sebaceous gland duct
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• mild at 14 days of age
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• at 14 days with prominent large basophilic keratohyalin granules
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• skin wrinkling appears before the majority of hair is lost, and it progresses with age
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endocrine/exocrine glands
growth/size/body
dermal cyst
(
J:156542
)
|
• develop from keratinocyte remnants that surrounded the dermal papilla
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limbs/digits/tail
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• at 6 months of age mice display overgrown nails that curve under the foot pad (onychogryposis)
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