Analysis Tools
mortality/aging
|
• almost half died within the first 3 weeks after birth and those that survived had a normal lifespan
• died suddenly without any severe sick appearance
|
growth/size/body
|
• 60% that of wild-type
|
immune system
|
• slightly less developed medulla
|
small thymus
(
J:98965
)
|
• detected at birth and persisted through the age of 5 weeks
|
|
• the number of cells in the thymus was about one quarter to half of that of controls
|
|
• decreased lymphoid cell population, however no significant differences in the myeloid components, in the composition of T and B cell populations, and platelet and red blood cell counts
|
small spleen
(
J:98965
)
|
• appeared small in infancy, however became proportional to body size later in life
|
hematopoietic system
|
• slightly less developed medulla
|
small thymus
(
J:98965
)
|
• detected at birth and persisted through the age of 5 weeks
|
|
• the number of cells in the thymus was about one quarter to half of that of controls
|
|
• decreased lymphoid cell population, however no significant differences in the myeloid components, in the composition of T and B cell populations, and platelet and red blood cell counts
|
small spleen
(
J:98965
)
|
• appeared small in infancy, however became proportional to body size later in life
|
endocrine/exocrine glands
|
• slightly less developed medulla
|
small thymus
(
J:98965
)
|
• detected at birth and persisted through the age of 5 weeks
|
|
• the number of cells in the thymus was about one quarter to half of that of controls
|
