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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(GFAP)7Mes
transgene insertion 7, Albee Messing
MGI:3581820
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(GFAP)7Mes/0 involves: FVB/N MGI:3581823


Genotype
MGI:3581823
tg1
Allelic
Composition		 Tg(GFAP)7Mes/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal astrocyte morphology ( J:99256 )
• astrocytes are enlarged and contain large eosinophilic aggregations resembling Rosenthal fibers; however unlike mice from high expressing lines mice from low expressing lines have normal life spans

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Alexander disease DOID:4252 OMIM:203450
 J:99256




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory