Phenotypes associated with this allele

• Allele Symbol: Senp1^m1Mku
• Allele Name: mutation 1, Michael R Kuehn
• Allele ID: MGI:3582213
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Senp1^m1Mku/Senp1^m1Mku	involves: 129	MGI:3582295

Genotype
MGI:3582295

hm1

• Allelic Composition: Senp1^m1Mku/Senp1^m1Mku
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality ( J:88845 )

lethality throughout fetal growth and development, complete penetrance ( J:99175 )

• death between E12.5 and E14.5, showing pooling of blood in the trunk region

embryo

abnormal placental labyrinth vasculature morphology ( J:99175 )

• labyrinth at E12.5 exhibits a significant reduction in both maternal and fetal blood spaces, fetal vessels that were widely separated from maternal blood sinuses, and appears to contain excess trophoblast

cellular

abnormal cell death ( J:99175 )

• exhibit widespread cell death at E13.5

cardiovascular system

abnormal placental labyrinth vasculature morphology ( J:99175 )

• labyrinth at E12.5 exhibits a significant reduction in both maternal and fetal blood spaces, fetal vessels that were widely separated from maternal blood sinuses, and appears to contain excess trophoblast