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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
St8sia4tm1Crem
targeted mutation 1, Harold Cremer
MGI:3582251
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
St8sia4tm1Crem/St8sia4tm1Crem involves: 129P2/OlaHsd * C57BL/6J MGI:3582290


Genotype
MGI:3582290
hm1
Allelic
Composition
St8sia4tm1Crem/St8sia4tm1Crem
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St8sia4tm1Crem mutation (0 available); any St8sia4 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• adult, but not young, homozygous null mice exhibit impaired long term potentiation in hippocampal CA1 synapses but not CA3 synapses
• adult, but not young, homozygous null mice exhibit impaired long term depression in hippocampal CA1 synapses





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory