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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Spsb2tm1Nch
targeted mutation 1, S E Nicholson
MGI:3582298
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Spsb2tm1Nch/Spsb2tm1Nch involves: C57BL/6 MGI:3582530
ht2
 		Spsb2tm1Nch/Spsb2+ involves: C57BL/6 MGI:3582531


Genotype
MGI:3582530
hm1
Allelic
Composition		 Spsb2tm1Nch/Spsb2tm1Nch
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spsb2tm1Nch mutation (0 available); any Spsb2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
thrombocytopenia ( J:99226 )
• very mild thrombocytopenia showing a 25% decrease in circulating platelets due to the production of fewer platelets per megakaryocyte, however hematopoiesis was normal

homeostasis/metabolism




Genotype
MGI:3582531
ht2
Allelic
Composition		 Spsb2tm1Nch/Spsb2+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spsb2tm1Nch mutation (0 available); any Spsb2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory