All Phenotypes Smarcc2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Smarcc2⁺
wild type
MGI:3582357

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Smarcc2^em1(IMPC)J/Smarcc2⁺	C57BL/6NJ-Smarcc2^em1(IMPC)J/Mmjax	MGI:6696910
cn2	Pax6^tm2Pgr/Pax6^tm2Pgr Smarcc2^tm1.1Stoy/Smarcc2⁺ Emx1^tm1(cre)Krj/Emx1⁺	involves: 129S1/Sv * 129S2/SvPas * C57BL/6	MGI:5504443

Allelic Composition	Smarcc2^em1(IMPC)J/Smarcc2⁺
Genetic Background	C57BL/6NJ-Smarcc2^em1(IMPC)J/Mmjax

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarcc2^em1(IMPC)J mutation (2 available); any Smarcc2 mutation (56 available)

Data Sources

IMPC Data for Smarcc2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased thigmotaxis ( J:211773 )

IMPC - JAX

cardiovascular system

decreased heart rate ( J:211773 )

IMPC - JAX

prolonged RR interval ( J:211773 )

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

hematopoietic system

increased mean corpuscular volume ( J:211773 )

IMPC - JAX

Allelic Composition	Pax6^tm2Pgr/Pax6^tm2Pgr Smarcc2^tm1.1Stoy/Smarcc2⁺ Emx1^tm1(cre)Krj/Emx1⁺
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1^tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)
Pax6^tm2Pgr mutation (1 available); any Pax6 mutation (94 available)
Smarcc2^tm1.1Stoy mutation (0 available); any Smarcc2 mutation (56 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:197141 )

N	• mice exhibit normal cortical surface at P8 and numbers of Tbr2+ intermediate progenitors at E14.5

abnormal neuron number ( J:197141 )

• mice exhibit increased production of Cux1+ upper layer identity neurons

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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