Phenotypes associated with this allele

• Allele Symbol: Pou4f2^tm1Rsd
• Allele Name: targeted mutation 1, Michael G Rosenfeld
• Allele ID: MGI:3582493
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pou4f2^tm1Rsd/Pou4f2^tm1Rsd	involves: 129S4/SvJae	MGI:3583886

Genotype
MGI:3583886

hm1

• Allelic Composition: Pou4f2^tm1Rsd/Pou4f2^tm1Rsd
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal superior colliculus morphology ( J:33502 )

• disorganized morphology specifically subtle differences in the cell density and the laminar organization that are particularly apparent in the stratum zonale

retina ganglion cell degeneration ( J:33502 )

• a loss of approximately 60-70% of retinal ganglion cells in P17-P120 mice

• count profiles in the ganglion cell layer of neonatal (P0) retina are normal

vision/eye

retina ganglion cell degeneration ( J:33502 )

• a loss of approximately 60-70% of retinal ganglion cells in P17-P120 mice

• count profiles in the ganglion cell layer of neonatal (P0) retina are normal