Analysis Tools
immune system
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• mice exhibited increased morbidity and mortality in a model of concanavalin A-mediated T cell-dependent autoimmune hepatitis which was dependent on presence of CD4+ T cells
• mice were more susceptible to MOG peptide-induced experimental autoimmune encephalopathy
• showed increased T cell proliferation and cytokine production in response to antigen-specific challenge
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• mutant T cells showed increased proliferation in response to concanavalin A in in vitro assay
• splenocytes from mutant mice exhibited increased T cell proliferation and increased cytokine production in response to concanavalin A in vitro
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hematopoietic system
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• mice exhibited increased morbidity and mortality in a model of concanavalin A-mediated T cell-dependent autoimmune hepatitis which was dependent on presence of CD4+ T cells
• mice were more susceptible to MOG peptide-induced experimental autoimmune encephalopathy
• showed increased T cell proliferation and cytokine production in response to antigen-specific challenge
|
|
• mutant T cells showed increased proliferation in response to concanavalin A in in vitro assay
• splenocytes from mutant mice exhibited increased T cell proliferation and increased cytokine production in response to concanavalin A in vitro
|
cellular
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• mutant T cells showed increased proliferation in response to concanavalin A in in vitro assay
• splenocytes from mutant mice exhibited increased T cell proliferation and increased cytokine production in response to concanavalin A in vitro
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