Analysis Tools
immune system
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• after treatment with anti-Fcer2a antibodies mice remain hyperreactive to ovalbumin compared to wild-type mice that exhibit decreased response
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• injection with anti-2,4-dinitrophenyl (DNP) IgE antibodies prior to exposure to DNP conjugated to ovalbumin does not result in production of OA-specific antibodies, unlike in wild-type mice; however, T and B cell development, thymus dependent antigen responses, serum IgE levels after infection with N. brasiliensis larvae, and spleen germinal centers are all similar to wild-type
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• after treatment with anti-Fcer2a antibodies mice continue to produce IgE and IgG1 in response to ovalbumin stimulation whereas wild-type mice exhibit a decrease in production
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• after treatment with anti-Fcer2a antibodies mice continue to produce cytokines in response to ovalbumin stimulation whereas wild-type mice exhibit a decrease in production
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hematopoietic system
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• after treatment with anti-Fcer2a antibodies mice continue to produce IgE and IgG1 in response to ovalbumin stimulation whereas wild-type mice exhibit a decrease in production
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