All Phenotypes Tg(Mef2c-cre)1Blk MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Mef2c-cre)1Blk
transgene insertion 1, Brian L Black
MGI:3583679

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Mef2c-cre)1Blk/0	involves: C57BL/6NTac	MGI:5316091

Allelic Composition	Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Mef2c-cre)1Blk/0
Genetic Background	involves: C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfl2^tm1Itl mutation (1 available); any Cfl2 mutation (19 available)
Tg(Mef2c-cre)1Blk mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:182571 )

• mice die between P7 and P12

muscle

abnormal Z line morphology ( J:182571 )

• dissolving

abnormal skeletal muscle morphology ( J:182571 )

• accumulation of F-actin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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