Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ntrk2tm1Ddg targeted mutation 1, David D Ginty MGI:3583735 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• viable and fertile, with no obvious behavioral abnormalities, however NMPP1, a derivative of the general kinase inhibitor PP1, inhibits neurotrophin signaling in neurons unlike in wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E13, female mice exposed to 1NMPP1 exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice
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• at E13, female mice exposed to 1NMPP1 exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice
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• at E13, female mice exposed to 1NMPP1 exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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