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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Xisttm1Sado
targeted mutation 1, Takashi Sado
MGI:3583749
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tsixtm1Enl/Tsix+
Xisttm1Sado/Xist+ 		involves: 129S4/SvJae MGI:3603005


Genotype
MGI:3603005
cx1
Allelic
Composition		 Tsixtm1Enl/Tsix+
Xisttm1Sado/Xist+
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsixtm1Enl mutation (1 available); any Tsix mutation (57 available)
Xisttm1Sado mutation (1 available); any Xist mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:99399 )
• females that have both mutations on the paternal X chromosome die soon after implantation; however, females that have both mutations on the maternal X chromosome are viable and fertile




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory