Phenotypes associated with this allele

• Allele Symbol: Polh^tm1Fmh
• Allele Name: targeted mutation 1, Fumio Hanaoka
• Allele ID: MGI:3583930
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Polh^tm1Fmh/Polh^tm1Fmh	involves: C57BL/6	MGI:3586812

Genotype
MGI:3586812

hm1

• Allelic Composition: Polh^tm1Fmh/Polh^tm1Fmh
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal B cell physiology ( J:99721 )

• hypermutation in J_H4 introns and in S mu regions displays a marked decrease in mutations of A and T bases and an increase in mutations of C and G; however, B and T cell numbers and class switch recombination in B cells are normal

hematopoietic system

abnormal B cell physiology ( J:99721 )

• hypermutation in J_H4 introns and in S mu regions displays a marked decrease in mutations of A and T bases and an increase in mutations of C and G; however, B and T cell numbers and class switch recombination in B cells are normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
xeroderma pigmentosum variant type		DOID:0110847	OMIM:278750	J:99721