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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ewsr1tm1(ERG)Thr
targeted mutation 1, Terence H Rabbitts
MGI:3584017
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ewsr1tm1(ERG)Thr/Ewsr1+
Rag1tm1(cre)Thr/Rag1+ 		involves: 129S/SvEv MGI:3603039


Genotype
MGI:3603039
cn1
Allelic
Composition		 Ewsr1tm1(ERG)Thr/Ewsr1+
Rag1tm1(cre)Thr/Rag1+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ewsr1tm1(ERG)Thr mutation (0 available); any Ewsr1 mutation (93 available)
Rag1tm1(cre)Thr mutation (0 available); any Rag1 mutation (123 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased leukemia incidence ( J:98679 )
• mutant mice develop leukemia involving T cells with infiltrating lymphoblasts in the bone marrow, liver, and kidney

immune system
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased lymphocyte cell number ( J:98679 )
• associated with leukemia

hematopoietic system
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased lymphocyte cell number ( J:98679 )
• associated with leukemia

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory