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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lmo2tm4Thr
targeted mutation 4, Terence H Rabbitts
MGI:3584123
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lmo2tm4Thr/Lmo2tm4Thr involves: 129S/SvEv MGI:3584426
cn2
 		Lmo2tm3Thr/Lmo2tm4Thr
Rag1tm1(cre)Thr/Rag1+ 		involves: 129S/SvEv MGI:3584438
cn3
 		Lmo2tm3Thr/Lmo2tm4Thr
Tg(Lck-cre)1Thr/0 		involves: 129S/SvEv MGI:3584439
cn4
 		Lmo2tm3Thr/Lmo2tm4Thr
Cd19tm1(cre)Thr/Cd19+ 		involves: 129S/SvEv MGI:3584440


Genotype
MGI:3584426
hm1
Allelic
Composition		 Lmo2tm4Thr/Lmo2tm4Thr
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo2tm4Thr mutation (0 available); any Lmo2 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3584438
cn2
Allelic
Composition		 Lmo2tm3Thr/Lmo2tm4Thr
Rag1tm1(cre)Thr/Rag1+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo2tm3Thr mutation (0 available); any Lmo2 mutation (31 available)
Lmo2tm4Thr mutation (0 available); any Lmo2 mutation (31 available)
Rag1tm1(cre)Thr mutation (0 available); any Rag1 mutation (123 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:86869 )
N
• mutant mice are viable and exhibit no hematopoietic defects, with normal bone marrow, spleen and thymus cell counts

immune system
immune system phenotype ( J:86869 )
N
• normal T and B lymphoid development




Genotype
MGI:3584439
cn3
Allelic
Composition		 Lmo2tm3Thr/Lmo2tm4Thr
Tg(Lck-cre)1Thr/0
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo2tm3Thr mutation (0 available); any Lmo2 mutation (31 available)
Lmo2tm4Thr mutation (0 available); any Lmo2 mutation (31 available)
Tg(Lck-cre)1Thr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:86869 )
N
• mutant mice are viable and exhibit no hematopoietic defects, with normal bone marrow, spleen and thymus cell counts

immune system
immune system phenotype ( J:86869 )
N
• normal T and B lymphoid development




Genotype
MGI:3584440
cn4
Allelic
Composition		 Lmo2tm3Thr/Lmo2tm4Thr
Cd19tm1(cre)Thr/Cd19+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Thr mutation (0 available); any Cd19 mutation (60 available)
Lmo2tm3Thr mutation (0 available); any Lmo2 mutation (31 available)
Lmo2tm4Thr mutation (0 available); any Lmo2 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:86869 )
N
• mutant mice are viable and exhibit no hematopoietic defects, with normal bone marrow, spleen and thymus cell counts

immune system
immune system phenotype ( J:86869 )
N
• normal T and B lymphoid development




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory