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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hipk1tm1Mak
targeted mutation 1, Tak Wah Mak
MGI:3584135
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hipk1tm1Mak/Hipk1tm1Mak involves: 129P2/OlaHsd * C57BL/6 MGI:3603203


Genotype
MGI:3603203
hm1
Allelic
Composition		 Hipk1tm1Mak/Hipk1tm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hipk1tm1Mak mutation (1 available); any Hipk1 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:99823 )
• 14 or 17 weeks after skin exposure to DMBA fewer tumors are seen and no malignant tumors are found in homozygous mice
• no spontaneous tumors are found through 1 year of age

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:99823 )
• 14 or 17 weeks after skin exposure to DMBA fewer tumors are seen and no malignant tumors are found in homozygous mice
• no spontaneous tumors are found through 1 year of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory