About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gria2tm1Rlh
targeted mutation 1, Richard L Huganir
MGI:3584143
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gria2tm1Rlh/Gria2tm1Rlh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3589567


Genotype
MGI:3589567
hm1
Allelic
Composition		 Gria2tm1Rlh/Gria2tm1Rlh
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria2tm1Rlh mutation (1 available); any Gria2 mutation (79 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
impaired synaptic plasticity ( J:99813 )
• following high-frequency stimulation on the cerebellum slice culture, no increase in the rectification ratio was observed, indicating that calcium-permeable AMPA receptor plasticity (CARP) does not occur in these mutant mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory