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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nos1tm1Enik
targeted mutation 1, Grigori Enikolopov
MGI:3584262
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nos1tm1Enik/Nos1tm1Enik involves: 129X1/SvJ * C57BL/6 MGI:3590237


Genotype
MGI:3590237
hm1
Allelic
Composition		 Nos1tm1Enik/Nos1tm1Enik
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos1tm1Enik mutation (0 available); any Nos1 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron differentiation ( J:99879 )
• increased neuronal proliferation is seen in the subventricular zone (23.7%), rostral migratory stream (41.8%), dentate gyrus (32.7%), and olfactory bulb (19.9%) with some cells in the rostral migratory stream appearing to migrate towards the cortex

cellular
abnormal neuron differentiation ( J:99879 )
• increased neuronal proliferation is seen in the subventricular zone (23.7%), rostral migratory stream (41.8%), dentate gyrus (32.7%), and olfactory bulb (19.9%) with some cells in the rostral migratory stream appearing to migrate towards the cortex




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory