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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Amd1tm1Kiga
targeted mutation 1, Kazuei Igarashi
MGI:3586494
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Amd1tm1Kiga/Amd1tm1Kiga involves: 129P2/OlaHsd * C57BL/6 MGI:3586724


Genotype
MGI:3586724
hm1
Allelic
Composition		 Amd1tm1Kiga/Amd1tm1Kiga
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amd1tm1Kiga mutation (1 available); any Amd1 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:99895 )
• homozygous embryos are present at E3.5 but absent by E6.5

embryo
embryonic growth arrest ( J:99895 )
• blastocysts isolated at E3.5 fail to grow in culture unless supplemented with spermidine




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory