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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Thy1tm1Rjmo
targeted mutation 1, R J Morris
MGI:3586862
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Thy1tm1Rjmo/Thy1tm1Rjmo involves: 129/Sv * C57BL/6 MGI:3589777


Genotype
MGI:3589777
hm1
Allelic
Composition		 Thy1tm1Rjmo/Thy1tm1Rjmo
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thy1tm1Rjmo mutation (2 available); any Thy1 mutation (211 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:31610 )
• strong inhibition of LTP in the dentate gyrus but not in CA1, however spatial learning as assessed in the watermaze is unimpaired

respiratory system
pulmonary fibrosis ( J:99951 )
• marked increase in severity of lung fibrosis and more extensive collagen deposition in response to intratracheal bleomycin compared to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory