Phenotypes associated with this allele

• Allele Symbol: Cks2^tm1Sir
• Allele Name: targeted mutation 1, Steven I Reed
• Allele ID: MGI:3586897
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cks2^tm1Sir/Cks2^tm1Sir	Not Specified	MGI:3607508

Genotype
MGI:3607508

hm1

• Allelic Composition: Cks2^tm1Sir/Cks2^tm1Sir
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

azoospermia ( J:99997 )

♂

multinucleated giant male germ cells ( J:99997 )

♂ • multinucleated spermatids are seen in some tubules

abnormal female meiosis ( J:99997 )

♀ • meiosis arrests at metaphase I; however ovary morphology appears normal

arrest of male meiosis ( J:99997 )

♂ • meiosis arrests at metaphase I during the first wave of spermatogenesis

reproductive system

azoospermia ( J:99997 )

♂

multinucleated giant male germ cells ( J:99997 )

♂ • multinucleated spermatids are seen in some tubules

abnormal female meiosis ( J:99997 )

♀ • meiosis arrests at metaphase I; however ovary morphology appears normal

arrest of male meiosis ( J:99997 )

♂ • meiosis arrests at metaphase I during the first wave of spermatogenesis

testicular atrophy ( J:99997 )

♂

female infertility ( J:99997 )

♀

male infertility ( J:99997 )

♂

endocrine/exocrine glands

testicular atrophy ( J:99997 )

♂