Phenotypes associated with this allele

• Allele Symbol: Atg7^tm1.1Tchi
• Allele Name: targeted mutation 1.1, Tomoki Chiba
• Allele ID: MGI:3587771
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atg7^tm1.1Tchi/Atg7^tm1.1Tchi	involves: C57BL/6 * CBA * FVB/N	MGI:3590136

Genotype
MGI:3590136

hm1

• Allelic Composition: Atg7^tm1.1Tchi/Atg7^tm1.1Tchi
• Genetic Background: involves: C57BL/6 * CBA * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:100199 )

• die within one day after birth

• die earlier compared with controls under starvation conditions after caesarean delivery (13 hours vs. 21 hours in controls)

growth/size/body

decreased body weight ( J:100199 )

• seen at birth

cellular

abnormal intracellular organelle morphology ( J:100199 )

• autophagosomes are absent

homeostasis/metabolism

abnormal circulating amino acid level ( J:100199 )

• lower concentrations of essential and branched-chain amino acids in the sera at 10 hours after caesarean delivery