Phenotypes associated with this allele

• Allele Symbol: Slc44a2⁺
• Allele Name: wild type
• Allele ID: MGI:3588321
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Slc44a2^tm1.2Tec/Slc44a2^+	FVB.129(Cg)-Slc44a2^tm1.2Tec	MGI:5881799

Genotype
MGI:5881799

ht1

• Allelic Composition: Slc44a2^tm1.2Tec/Slc44a2⁺
• Genetic Background: FVB.129(Cg)-Slc44a2^tm1.2Tec

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal organ of Corti morphology ( J:239440 )

decreased cochlear outer hair cell number ( J:239440 )

• outer hair cells are missing in the basal turn of the organ of Corti

increased or absent threshold for auditory brainstem response ( J:239440 )

• elevated hearing threshold at 32 kHz at 4 months, however, hearing loss is minimal at 12 and 24kHz frequencies

nervous system

decreased cochlear outer hair cell number ( J:239440 )

• outer hair cells are missing in the basal turn of the organ of Corti

abnormal cochlear ganglion morphology ( J:239440 )

• decreased density of spiral ganglion cells in the basal turn of organ of Corti

• spiral ganglion cells in the basal turn of organ of Corti appear abnormal