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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata1tm9Sho
targeted mutation 9, Stuart H Orkin
MGI:3588564
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Gata1tm9Sho/Y involves: C57BL/6 MGI:3809766
ot2
 		Gata1tm9Sho/Y Not Specified MGI:3589732


Genotype
MGI:3809766
ot1
Allelic
Composition		 Gata1tm9Sho/Y
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm9Sho mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:132560 )
N
• in adults peripheral blood parameters and bone marrow and spleen blood cell populations are not significantly different from wild-type littermates
• at E17.5 and E18.5 peripheral blood parameters are normal




Genotype
MGI:3589732
ot2
Allelic
Composition		 Gata1tm9Sho/Y
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm9Sho mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
impaired hematopoiesis ( J:100411 )
• fetal liver cells from embryonic day 14.5 depleted of nonerythroid cells have diminished TIMP1 secretion compared with those of wildtype fetal liver cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory