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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sgk3ypc
ypc
MGI:3588656
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sgk3ypc/Sgk3ypc YPC MGI:3589376


Genotype
MGI:3589376
hm1
Allelic
Composition
Sgk3ypc/Sgk3ypc
Genetic
Background
YPC
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sgk3ypc mutation (0 available); any Sgk3 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• thin, short hairs
• at 3 days of age, the hair shafts are narrow and immature
• by 5 days of age hair medulla is disorganized
• although normal at birth, at 3 days of age homozygotes have abnormal hair follicles with small hair bulbs
• at 5 days of age the abnormal hair follicles are also shorter in length and have a reduced number of matrix cells
• reduced number of matrix cells by 5 days of age
• small hair bulbs at 3 days of age
• at 5 days of age the inner root sheath is decreased in thickness
• by 3 days of age the hair follicles lack uniform orientation
• at 5 days of age the outer root sheath is increased in thickness





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory