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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		tmgc46
Tennessee Mouse Genome Consortium 46
MGI:3589243
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		tmgc46/tmgc46 mixed MGI:3589396


Genotype
MGI:3589396
hm1
Allelic
Composition		 tmgc46/tmgc46
Genetic
Background		 mixed
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
tmgc46 mutation (1 available); any tmgc46 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:92490 )
• at 32kHz stimuli, no measurable ABR is detected at the highest SPL tested (95db)
• significantly increased threshold for ABR response to 16kHz and 8kHz stimuli
impaired hearing ( J:92490 )
• high frequency hearing loss with wide range component




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory