Phenotypes associated with this allele

• Allele Symbol: Dst^dt-38J
• Allele Name: dystonia musculorum 38 Jackson
• Allele ID: MGI:3589419
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dst^dt-38J/Dst^dt-38J	involves: BALB/cByJ * C57BL/6J	MGI:3589420

Genotype
MGI:3589420

hm1

• Allelic Composition: Dst^dt-38J/Dst^dt-38J
• Genetic Background: involves: BALB/cByJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:82238 )

• mutant mice are smaller than their unaffected littermates

reproductive system

reproductive system phenotype ( J:82238 )

N • although reproductive systems of both male and female mutants are normal, homozygous mice cannot mate because of their hind limb weakness

muscle

muscle spasm ( J:82238 )

• the hind limbs of homozygous mice exhibit intermittent spasms from about two weeks of age

behavior/neurological

weakness ( J:82238 )

• both front and, particularly, hind limbs of mutant mice exhibit obvious weakness from the age of about two weeks; however, a standard pathological examination revealed no abnormality of muscle morphology

abnormal posture ( J:82238 )

• from about two weeks of age, the hind limbs of mutant mice splay to the sides and their front paws turn inward