All Phenotypes Ndel1<tm2Shr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ndel1^tm2Shr
targeted mutation 2, Shinji Hirotsune
MGI:3589467

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ndel1^tm1.1Shr/Ndel1^tm2Shr	involves: 129S6/SvEvTac	MGI:3589750

Allelic Composition	Ndel1^tm1.1Shr/Ndel1^tm2Shr
Genetic Background	involves: 129S6/SvEvTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndel1^tm1.1Shr mutation (0 available); any Ndel1 mutation (40 available)
Ndel1^tm2Shr mutation (1 available); any Ndel1 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal telencephalon development ( J:100552 )

• dendritic extensions of postmiotic neurons in the cortical plate are irregular and fragmented

abnormal hippocampus pyramidal cell morphology ( J:100552 )

• mild partial splitting and diffuse pyramidal cells are seen in the CA3 and CA2 regions of the hippocampus

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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