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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		repro3
reproductive mutant 3, JAX Reproductive Mutagenisis Program
MGI:3590190
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		repro3/repro3 involves: C3HeB/FeJ * C57BL/6J MGI:3697913


Genotype
MGI:3697913
hm1
Allelic
Composition		 repro3/repro3
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
oligozoospermia ( J:117563 )
• epididymal sperm concentration is (1.7 +/- 1.7) x 106 sperm/ml
• however, testes and seminal vesicle weights are similar to wild-type
teratozoospermia ( J:117563 )
• all sperm have abnormal head and/or tail morphology
abnormal sperm flagellum morphology ( J:117563 )
• abnormal sperm tail morphology is observed
absent sperm mitochondrial sheath ( J:117563 )
• axonemal profiles lack the associated mitochondrial sheath
short sperm flagellum ( J:117563 )
• sperm tails are short
abnormal sperm head morphology ( J:117563 )
• abnormally shaped sperm heads are observed
abnormal sperm nucleus morphology ( J:117563 )
• abnormal hammerhead nuclear shapes are observed
abnormal spermatid morphology ( J:117563 )
• some spermatids display abnormal hammerhead nuclear shapes and tail elongation is impaired
immotile sperm ( J:117563 )
• immobile sperm
impaired fertilization ( J:117563 )
• sperm fail to fertilize oocytes in in vitro fertilization tests

cellular
oligozoospermia ( J:117563 )
• epididymal sperm concentration is (1.7 +/- 1.7) x 106 sperm/ml
• however, testes and seminal vesicle weights are similar to wild-type
teratozoospermia ( J:117563 )
• all sperm have abnormal head and/or tail morphology
abnormal sperm flagellum morphology ( J:117563 )
• abnormal sperm tail morphology is observed
absent sperm mitochondrial sheath ( J:117563 )
• axonemal profiles lack the associated mitochondrial sheath
short sperm flagellum ( J:117563 )
• sperm tails are short
abnormal sperm head morphology ( J:117563 )
• abnormally shaped sperm heads are observed
abnormal sperm nucleus morphology ( J:117563 )
• abnormal hammerhead nuclear shapes are observed
abnormal spermatid morphology ( J:117563 )
• some spermatids display abnormal hammerhead nuclear shapes and tail elongation is impaired
immotile sperm ( J:117563 )
• immobile sperm




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory