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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Elf1tm1Jml
targeted mutation 1, Jeffrey M Leiden
MGI:3590647
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Elf1tm1Jml/Elf1tm1Jml Not Specified MGI:3608710


Genotype
MGI:3608710
hm1
Allelic
Composition		 Elf1tm1Jml/Elf1tm1Jml
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elf1tm1Jml mutation (0 available); any Elf1 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell physiology ( J:100734 )
• FACS analysis shows decreased CD1D1 expression on splenic B cells and real-time PCR shows only 30% of wild-type Cd1d1 in splenic B cells although CD1D1 expression appears normal in thymocytes, splenic T cells, fibroblasts, macrophages, and dendritic cells

hematopoietic system
abnormal B cell physiology ( J:100734 )
• FACS analysis shows decreased CD1D1 expression on splenic B cells and real-time PCR shows only 30% of wild-type Cd1d1 in splenic B cells although CD1D1 expression appears normal in thymocytes, splenic T cells, fibroblasts, macrophages, and dendritic cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory