mortality/aging
• mice exposed to hyperoxic conditions exhibit delayed mortality compared to similarly treated wild-type mice
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immune system
• exhibit reduced hydrogen peroxide compared to in similarly treated wild-type mice
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homeostasis/metabolism
N |
• mice fed a high fat diet, exhibit normal HDL concentrations
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• under hyperoxic conditions, mice exhibit decreased response; less severe lung injury, including reduced increase in lung wet:dry weight ratio, necrosis of bronchiolar epithelium, perivascular and alveolar edema, and number of inflammatory cells in the airspaces; and delayed mortality compared with wild-type mice
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cardiovascular system
N |
• mice fed a high fat diet develop normal atherosclerotic lesions
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hematopoietic system
• exhibit reduced hydrogen peroxide compared to in similarly treated wild-type mice
|