About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pag1tm1Kplm
targeted mutation 1, Kong-Peng Lam
MGI:3604217
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pag1tm1Kplm/Pag1tm1Kplm involves: 129P2/OlaHsd * C57BL/6 MGI:3606982


Genotype
MGI:3606982
hm1
Allelic
Composition
Pag1tm1Kplm/Pag1tm1Kplm
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pag1tm1Kplm mutation (0 available); any Pag1 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• a significant increase in thymocyte numbers is seen; however, the proportion of different T cell populations is normal, no increase is seen in peripheral B and T cell numbers T cell receptor signaling and T cell dependent immune responses are normal, and mice do not display any increase autoimmunity

hematopoietic system
• a significant increase in thymocyte numbers is seen; however, the proportion of different T cell populations is normal, no increase is seen in peripheral B and T cell numbers T cell receptor signaling and T cell dependent immune responses are normal, and mice do not display any increase autoimmunity

endocrine/exocrine glands
• a significant increase in thymocyte numbers is seen; however, the proportion of different T cell populations is normal, no increase is seen in peripheral B and T cell numbers T cell receptor signaling and T cell dependent immune responses are normal, and mice do not display any increase autoimmunity





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory