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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Craddtm1Mak
targeted mutation 1, Tak W Mak
MGI:3604302
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Craddtm1Mak/Craddtm1Mak involves: 129 * C57BL/6 MGI:3715866


Genotype
MGI:3715866
hm1
Allelic
Composition		 Craddtm1Mak/Craddtm1Mak
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Craddtm1Mak mutation (0 available); any Cradd mutation (106 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased physiological sensitivity to xenobiotic ( J:101402 )
• thymocytes have increased sensitivity to cytotoxin agents such as dexamethasone, gamma-radiation, etoposide, and straurosporine

cellular
increased cellular sensitivity to gamma-irradiation ( J:101402 )
• increased sensitivity to gamma-radiation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory