hematopoietic system
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age
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• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age
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• 2 of 4 homozygotes exhibit increased extramedullary hematopoiesis of the spleen at 300 days of age
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immune system
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age
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• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age
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renal/urinary system
• the size and weight of the kidney is increased in 2 of 2 males at 300 days of age
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endocrine/exocrine glands
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age
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growth/size/body
• the size and weight of the kidney is increased in 2 of 2 males at 300 days of age
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• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age
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