Phenotypes associated with this allele

• Allele Symbol: B3galt2^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:3604457
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	B3galt2^tm1Dgen/B3galt2^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	MGI:3606681

Genotype
MGI:3606681

hm1

• Allelic Composition: B3galt2^tm1Dgen/B3galt2^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased coping response ( J:101679 )

• spend significantly more time immobile in the Tail Suspension test, indicating a possible depression-like phenotype

decreased anxiety-related response ( J:101679 )

• spend significantly more time in the central region of the open field, indicating decreased anxiety

increased startle reflex ( J:101679 )

• exhibit enhanced startle responses to sound stimuli at 110 db and 120 db

impaired coordination ( J:101679 )

• exhibit impaired activity on the rotarod test, falling from accelerating rotarod at slower speeds than wildtype

increased locomotor activity ( J:101679 )

• exhibit an increase in total distance traveled in the Open Field test

growth/size/body

decreased body weight ( J:101679 )

• body weight of homozygous males is decreased compared to controls