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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Htr7tm1Dgen
targeted mutation 1, Deltagen
MGI:3604477
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Htr7tm1Dgen/Htr7tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606454


Genotype
MGI:3606454
hm1
Allelic
Composition		 Htr7tm1Dgen/Htr7tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htr7tm1Dgen mutation (1 available); any Htr7 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
enhanced coordination ( J:101679 )
• enhanced motor performance on a rotorod test
• able to stay on a rotarod at significantly faster speeds
increased thermal nociceptive threshold ( J:101679 )
• significantly increased thermal response latency during hot plate tests
• significantly decreased thermal response latency during tail flick tests




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory