Phenotypes associated with this allele

• Allele Symbol: Frzb^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:3604496
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Frzb^tm1Dgen/Frzb^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	MGI:3606629

Genotype
MGI:3606629

hm1

• Allelic Composition: Frzb^tm1Dgen/Frzb^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased depression-related behavior ( J:101679 )

• homozygous mice exhibited significantly decreased time immobile during tail suspension testing, which may be associated with a decreased depression-like state

impaired coordination ( J:101679 )

• homozygous mice fell from the rotarod at significantly slower speeds, indicating a possible decreased motor performance

increased thermal nociceptive threshold ( J:101679 )

• homozygous mice exhibited a significant increase in thermal response latency during tail flick and hot plate testing, indicating a possible increased pain threshold