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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Esrrgtm1Dgen
targeted mutation 1, Deltagen
MGI:3604501
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Esrrgtm1Dgen/Esrrgtm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606615
ht2
 		Esrrgtm1Dgen/Esrrg+ involves: 129P2/OlaHsd * C57BL/6 MGI:3606616


Genotype
MGI:3606615
hm1
Allelic
Composition		 Esrrgtm1Dgen/Esrrgtm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esrrgtm1Dgen mutation (1 available); any Esrrg mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:101679 , J:156955 )
• homozygous mutant mice do not survive to weaning age (J:101679)
• death occurs by 2 days of age (J:156955)
• homozygotes born in expected ratios (J:156955)




Genotype
MGI:3606616
ht2
Allelic
Composition		 Esrrgtm1Dgen/Esrrg+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esrrgtm1Dgen mutation (1 available); any Esrrg mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperekplexia ( J:101679 )
• heterozygous mutant mice exhibited a significant increase in overall startle amplitude, indicating a possible hypersensitivity to sound-induced motor reflex in these mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory