Analysis Tools
homeostasis/metabolism
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• energy expenditure is increased
• however, respiratory exchange ratio is unchanged
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• males and females are lean on regular chow and are resistant to high fat diet weight gain
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• on a high fat diet, glucose response in females is 9% lower than in controls
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• on a high fat diet, fasting insulin levels in females are 76% lower
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• plasma adiponectin levels are elevated in females on normal chow
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• regardless of diet, plasma cholesterol levels are reduced
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• on normal chow or after a high fat diet, liver triglyceride levels are lower
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adipose tissue
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• after 11 weeks on a high fat diet
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• at 8 weeks on a high fat diet, females brown adipose tissue has less vacuoles
• brown adipose tissue contains more mitochondria
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• at 8 weeks on a high fat diet, females have smaller adipocytes
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• after 11 weeks on a high fat diet, males and females have less reproductive and perirenal white adipose tissue
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• after 11 weeks on a high fat diet, males and females have less reproductive white adipose tissue
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• after 11 weeks on a high fat diet, males and females have less perirenal white adipose tissue
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• at 8 weeks on a high fat diet, females have a lower total body fat mass that controls
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behavior/neurological
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• 28% increase in food intake
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• during light and dark phase, locomotor activity is increased at the expense of time spent in a corner
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growth/size/body
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• at 8 weeks on a high fat diet, females have a moderately lower lean body mass
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• males and females are lean on regular chow and are resistant to high fat diet weight gain
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nervous system
reproductive system
endocrine/exocrine glands
liver/biliary system
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• on normal chow or after a high fat diet, liver triglyceride levels are lower
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