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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pofut2Gt(OST231463)Lex
gene trap OST231463, Lexicon Genetics
MGI:3604508
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pofut2Gt(OST231463)Lex/Pofut2Gt(OST231463)Lex involves: 129S5/SvEvBrd MGI:3609757
ht2
 		Pofut2Gt(OST231463)Lex/Pofut2Gt(RST434)Byg involves: 129P2/OlaHsd * 129S5/SvEvBrd MGI:4881927


Genotype
MGI:3609757
hm1
Allelic
Composition		 Pofut2Gt(OST231463)Lex/Pofut2Gt(OST231463)Lex
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pofut2Gt(OST231463)Lex mutation (2 available); any Pofut2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:165751 )
• homozygous embryos died after implantation and before E10.5, a time period during which gastrulation and early organogenesis occurs
• phenotype is stated to be similar to that of Pofut2Gt(RST434)Byg homozygote; however no data are presented in J:165751




Genotype
MGI:4881927
ht2
Allelic
Composition		 Pofut2Gt(OST231463)Lex/Pofut2Gt(RST434)Byg
Genetic
Background		 involves: 129P2/OlaHsd * 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pofut2Gt(OST231463)Lex mutation (2 available); any Pofut2 mutation (29 available)
Pofut2Gt(RST434)Byg mutation (2 available); any Pofut2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:165751 )
• homozygous embryos died after implantation and before E10.5, a time period during which gastrulation and early organogenesis occurs
• phenotype is stated to be similar to that of Pofut2Gt(RST434)Byg homozygote; however no data are presented in J:165751




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory