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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scn3aGt(OST52130)Lex
gene trap OST52130, Lexicon Genetics
MGI:3604522
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Scn3aGt(OST52130)Lex/Scn3aGt(OST52130)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609666
ht2
 		Scn3aGt(OST52130)Lex/Scn3a+ involves: 129S5/SvEvBrd * C57BL/6J MGI:3609668


Genotype
MGI:3609666
hm1
Allelic
Composition		 Scn3aGt(OST52130)Lex/Scn3aGt(OST52130)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn3aGt(OST52130)Lex mutation (1 available); any Scn3a mutation (111 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:103485 )
• greatly reduced viability of homozygotes with only 2 homozygotes detected, one of which died within 3 weeks of birth

growth/size/body
decreased body size ( J:103485 )

behavior/neurological




Genotype
MGI:3609668
ht2
Allelic
Composition		 Scn3aGt(OST52130)Lex/Scn3a+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn3aGt(OST52130)Lex mutation (1 available); any Scn3a mutation (111 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory