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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Capn7tm1Dgen
targeted mutation 1, Deltagen
MGI:3604530
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Capn7tm1Dgen/Capn7tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606700
ht2
 		Capn7tm1Dgen/Capn7+ involves: 129P2/OlaHsd * C57BL/6 MGI:3606701


Genotype
MGI:3606700
hm1
Allelic
Composition		 Capn7tm1Dgen/Capn7tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn7tm1Dgen mutation (1 available); any Capn7 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:101679 )
• frequently die before weaning but some homozygotes do survive

growth/size/body
decreased body weight ( J:101679 )
• body weight is lower
• total tissue mass reduced




Genotype
MGI:3606701
ht2
Allelic
Composition		 Capn7tm1Dgen/Capn7+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn7tm1Dgen mutation (1 available); any Capn7 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased thermal nociceptive threshold ( J:101679 )
• increased thermal response latency in hot plate test




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory